COMPARE Results for S649890, Flavopiridol

Values for the National Cancer Institute Human Tumor Cell Line Screen

This calculation provided by the Developmental Therapeutics Program, DCTD, NCI

GI50 Results from the Synthetic Compound (December 1998 Release) Database
Searched 31796 samples
Minimum Number of Cell Lines in the Calculation 40
Minumum Variance of Hit data: 0.02
Cell Lines with the HIGHEST input values are the most inhibited

Rank NSC Compound Name High Conc. Average GI50 # cell lines Variance # of Exp PCC Mean Graph
1 649890 Flavopiridol 1.0E-06 M 7.5E-08 M 60 0.081 2 1.000
2 649890 Flavopiridol 1.0E-04 M 5.4E-08 M 60 0.082 6 0.679
3 666096 Olomoucine 1.0E-04 M 5.2E-05 M 60 0.036 5 0.670
4 85561 1.0E-04 M 2.2E-05 M 51 0.189 1 0.655
5 658086 1.0E-04 M 6.6E-05 M 60 0.050 2 0.643
6 649311 1.0E-04 M 3.3E-05 M 44 0.106 2 0.631
7 658082 1.0E-04 M 5.0E-05 M 60 0.086 2 0.625
8 664704 kenpaullone 1.0E-04 M 4.2E-05 M 57 0.311 2 0.619
9 631391 1.0E-04 M 3.2E-05 M 48 0.268 2 0.618
10 685828 1.0E-04 M 1.6E-05 M 57 0.149 1 0.613
11 651704 1.0E-04 M 4.7E-05 M 48 0.151 1 0.613
12 673347 Naphthalene, 1,4-bis(oxiranylmethoxy)- 1.0E-04 M 3.3E-06 M 59 0.201 1 0.601
13 657589 1.0E-04 M 4.6E-05 M 48 0.258 1 0.601
14 632820 1.0E-04 M 1.1E-05 M 47 0.076 1 0.596
15 642740 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihy 1.0E-04 M 5.1E-08 M 50 0.152 2 0.594
16 666974 1.0E-04 M 6.4E-05 M 57 0.050 1 0.594
17 624589 Claenone 1.0E+04 M 9.6E+02 M 45 0.169 1 0.593
18 653842 1.0E-04 M 5.7E-06 M 46 0.168 1 0.590
19 637215 cis-Dichlorobis-[1(2-hydroxyphenyl)-3-phenylpropan 1.0E-04 M 2.2E-05 M 48 0.053 1 0.587
20 658107 1.0E-04 M 7.6E-05 M 60 0.061 1 0.586
21 653501 1.0E-04 M 8.2E-05 M 41 0.033 1 0.584
22 634374 1.5E+02 u 3.7E+01 u 49 0.256 1 0.582
23 47714 C.I. Mordant Black 17, monosodium salt 1.0E-04 M 2.6E-05 M 58 0.129 2 0.580
24 657727 1.0E-04 M 2.0E-05 M 58 0.090 2 0.578
25 649612 1.0E-04 M 2.7E-05 M 49 0.071 1 0.576