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Screening Services

Cell Lines In The In Vitro Screen

Note: This is a list of the 60 human cancer cell lines used in the screen and maintained at NCI-Frederick. Additional lines evaluated for use in the screen and currently available are listed separately at the bottom of the page.

Please note the links for more information on the SNB-19, U251, NCI/ADR-RES, and MDA-MB-435 cell lines.

Cell Line Name Panel Name Doubling Time Inoculation Density
CCRF-CEM Leukemia 26.7 40000
HL-60(TB) Leukemia 28.6 40000
K-562 Leukemia 19.6 5000
MOLT-4 Leukemia 27.9 30000
RPMI-8226 Leukemia 33.5 20000
SR Leukemia 28.7 20000
A549/ATCC Non-Small Cell Lung 22.9 7500
EKVX Non-Small Cell Lung 43.6 20000
HOP-62 Non-Small Cell Lung 39 10000
HOP-92 Non-Small Cell Lung 79.5 20000
NCI-H226 Non-Small Cell Lung 61 20000
NCI-H23 Non-Small Cell Lung 33.4 20000
NCI-H322M Non-Small Cell Lung 35.3 20000
NCI-H460 Non-Small Cell Lung 17.8 7500
NCI-H522 Non-Small Cell Lung 38.2 20000
COLO 205 Colon 23.8 15000
HCC-2998 Colon 31.5 15000
HCT-116 Colon 17.4 5000
HCT-15 Colon 20.6 10000
HT29 Colon 19.5 5000
KM12 Colon 23.7 15000
SW-620 Colon 20.4 10000
SF-268 CNS 33.1 15000
SF-295 CNS 29.5 10000
SF-539 CNS 35.4 15000
SNB-19 CNS (For more Information) 34.6 15000
SNB-75 CNS 62.8 20000
U251 CNS (For more information) 23.8 7500
LOX IMVI Melanoma 20.5 7500
MALME-3M Melanoma 46.2 20000
M14 Melanoma 26.3 15000
MDA-MB-435 Melanoma (For more information) 25.8 15000
SK-MEL-2 Melanoma 45.5 20000
SK-MEL-28 Melanoma 35.1 10000
SK-MEL-5 Melanoma 25.2 10000
UACC-257 Melanoma 38.5 20000
UACC-62 Melanoma 31.3 10000
IGR-OV1 Ovarian 31 10000
OVCAR-3 Ovarian 34.7 10000
OVCAR-4 Ovarian 41.4 15000
OVCAR-5 Ovarian 48.8 20000
OVCAR-8 Ovarian 26.1 10000
NCI/ADR-RES Ovarian (For more information) 34 15000
SK-OV-3 Ovarian 48.7 20000
786-0 Renal 22.4 10000
A498 Renal 66.8 25000
ACHN Renal 27.5 10000
CAKI-1 Renal 39 10000
RXF 393 Renal 62.9 15000
SN12C Renal 29.5 15000
TK-10 Renal 51.3 15000
UO-31 Renal 41.7 15000
PC-3 Prostate 27.1 7500
DU-145 Prostate 32.3 10000
MCF7 Breast 25.4 10000
MDA-MB-231/ATCC Breast 41.9 20000
MDA-MB-468 Breast 62 2000
HS 578T Breast 53.8 20000
MDA-N
Not Available
Breast 22.5 15000
BT-549 Breast 53.9 20000
T-47D Breast 45.5 20000

Additional Lines

Cell Line Name Panel Name Doubling Time Inoculation Density
LXFL 529 Non-Small Cell Lung   10000
DMS 114 Small Cell Lung   20000
SHP-77 Small Cell Lung   40000
DLD-1 Colon   50000
KM20L2 Colon   10000
SNB-78 CNS   20000
XF 498 CNS   20000
RPMI-7951 Melanoma   20000
M19-MEL Melanoma   10000
RXF-631 Renal   10000
SN12K1 Renal   10000
P388 Leukemia   50000
P388/ADR Leukemia   50000